Hopedale is a town located in Worcester County, Massachusetts. It was first settled in 1660 and was officially incorporated in 1886. According to the United States Census Bureau, the town has a total area of 13.8 km² (5.3 mi²). 13.4 km² (5.2 mi²) of it is land and 0.4 km² (0.2 mi²) of it is water. The total area is 3.20% water.