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Sites about the defense mechanism of the body which are dependent on the humoral aspects of immunity as compared to the cell-mediated aspects which secrete Cytokines. Sites may include the mechanisms of interaction of antibody with antigen, as well as the cascade sequence that this invokes, through the complement system.

Sites may describe the molecular structure of antibodies, their classification and problems associated with their synthesis, such as the glycosylation of recombinant proteins, to mimic mammalian species, but are produced in plant cell host, "Plantibodies".

Sites [ Submit ]
Validated Antibody Database - Resource for searching and browsing commercial, academic and therapeutical monoclonal antibodies through gene name, accession number, taxonomy, ontology, disease, and amino acid sequences. Humanization bY Design - Resources describing the process of creating humanized antibodies, their uses and their history. Maintained by Birkbeck College, London, UK. Antibodies - Structure and Sequence - Attempts to summarize useful information on antibody structure and sequence. Provides a query interface to the Kabat antibody sequence data, general information on antibodies and crystal structures, and links. Conjugation of Monoclonal Antibodies - Straightforward procedures for conjugation of proteins (mainly antibodies) to fluorescent dyes. Monoclonal Antibodies - Introduction, uses (including in human medicine), problems and what may happen in the future. HLA Matching, Antibodies, and You - Tissue matching and antibody production, for patients undergoing a transplant. Antibodies and Therapy - Article on the history of vaccination, the role of the humoral response in organ and bone marrow transplantation, leukaemia and lymphoma, and rheumatoid disease. Includes links to laboratories at the Therapeutic Antibody Centre, Oxford, UK. Pluckthun, Andreas - Laboratory concentrating on protein engineering and directed molecular evolution, especially of immunoglobulins. Includes PDFs of molecular structures, publications since 1985, and contacts at the University of Zurich in Switzerland. Antibody Directory - A comprehensive directory of various antibodies, antigens, enzymes and proteins for molecular life sciences and biotechnology use.
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